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EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association
EPDA - European Parkinsons Disease Association
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Neuroprotection and Parkinson's

Slowing down or stopping the process of neurodegeneration remains one of the most important goals of current Parkinson’s research.  Considerable study is being undertaken to better understand the underlying disease mechanism, and to determine why the reduction in dopamine-producing brain cells occurs. 

Up until recently anti-Parkinson’s therapies were primarily focussed on improving symptoms of Parkinson’s. However, new insights into the causes and progression of the illness have led to the development of disease-modifying agents that may affect the natural progression of the condition.  The hope is that specific medicines can be developed to change some of the processes leading to cell death and so protect the remaining neurons.  These medicines fall largely into the following categories:

  • anti-oxidant – scavenging any harmful free-radical that may cause cell damage

  • anti-inflammatory – preventing harmful inflammation
  • anti-apoptotic - preventing the self-destruction of cells
  • anti-excitotoxic - preventing the process by which nerve cells are damaged and killed by various substances
  • pro-mitochondrial - supporting the mitochondria  which provide cells with energy. 

Did you know?

It is estimated that there are around 100 billion neurons in the human brain.
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