[Skip to content]

EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association
EPDA - European Parkinsons Disease Association
REWRITE TOMORROW
.

Research

Recent animal studies and one clinical trial suggest that exercise may help prevent or slow neurological deterioration, perhaps by producing protective brain chemicals called neurotrophic factors. A small study at the University of Pittsburgh found that those who exercised three times a week showed an improvement in balance and the ability to perform daily tasks. Other animal studies also show that exercise helps slow the loss of dopamine producing cells and so improves motor difficulties associated with Parkinson’s 1 2 3.

Following a 2005 study at the Harvard School of Public Health which concluded that young adult men who exercised vigorously at least twice a week reduced their risk of getting Parkinson’s later by 60%, further research is now under way to confirm whether exercise early in life might help prevent neurological degeneration4 .

A small study into the benefits of the Nintendo Wii at the Medical College of Georgia, USA5 , found that participants showed significant improvements in movement, fine motor skills, rigidity and energy levels.  Significantly, depression levels dropped to zero in those who took part

More research is needed into the duration and intensity of exercise but many believe that a regular programme should begin as soon as possible after diagnosis in order to achieve maximum benefit.


Did you know?

In some cases performing exercise routines can temporarily help with tremor, for example when bouncing a ball. Be aware, however, that the benefits usually do not last beyond the period of activity.

 


References



  1. Jakowec MW, Fisher B, Nixon K et al. Neuroplasticity in the MPTP-lesioned mouse and nonhuman primate. Ann NY Acad Sci 2003; 991: 298–301
  2. Tillerson J, Caudle WM, Reverón ME et al. Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson’s disease. Neuroscience 2003; 119 (3): 899–911
  3. Tillerson J, Cohen AD, Philhower J et al. Forced limb-use effects on the behavioral and neurochemical effects of 6-hydroxydopamine. J Neurosci 2001; 21(12): 4427–35
  4. Michael J. Zigmond, Judy L. Cameron, Rehana K. Leak, Karoly Mirnics, Vivienne A. Russell, Richard J. Smeyne, Amanda D. Smith.Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency. Parkinsonism & Related Disorders Vol 15 (3); S42-S45 (December 2009)
  5. The Nintendo Wii© and PD www.parkinson.org/NationalParkinsonFoundation/files/cd/cdf0b319-a28b-4082-bf07-64888dbd2c90.pdf

EPDA EPDA EPDA EPDA EPDA EPDA EPDA EPDA