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EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association EPDA - European Parkinsons Disease Association
EPDA - European Parkinsons Disease Association
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Essential tremor and Parkinson’s

ET and Parkinson’s are two separate, quite different conditions.  In contrast to ET and its postural or kinetic tremor coming on simultaneously in both upper limbs, Parkinson’s tremor is usually unilateral (i.e. one side only) and, in the majority of cases, starts in the hand as a rest tremor . That is, a tremor that occurs in a body part which is not voluntarily activated and is completely supported against gravity - for example, when sitting watching television with the arm resting at the side and the hand is seen to shake usually until the arm is moved intentionally. 

Another difference between ET and Parkinson’s is that head tremor is found in more than 30% of people with ET, yet is extremely rare in Parkinson’s.  However, it is important to note that, if shaking in Parkinson’s becomes violent, the head can manifest a secondary tremor as a passive consequence of such movements.

Parkinson’s tremor is also considered to be symptomatic in that it reflects known changes in the nervous system and, unlike ET, the disease is not generally inherited.

Because ET is not associated with any degenerative process in the brain itself, accompanying features of Parkinson’s, such as rigidity, bradykinesia or gait disturbance, are not seen.  For example, when an individual with a Parkinson’s tremor of the upper limb is observed to walk, invariably there is loss of normal arm swing.  This does not occur in ET.  Confusingly, however, cogwheel rigidity (that is the interruption of passive movement of a body part around a joint) is a feature of both Parkinson’s and ET.

Whilst careful clinical assessment usually allows a confident diagnostic separation between ET and Parkinson’s, similarities between the two conditions, such as cogwheel rigidity, often result in misdiagnosis.  Furthermore, as ET is relatively common, the two conditions can occur in the same individual.  Not surprisingly, there have been occasions when ET has been diagnosed ET as Parkinson’s and vice versa.  In particular, some American doctors are prone to call the postural tremor found in Parkinson’s ET.

It is vital to distinguish ET from Parkinson’s, both for prognostic purposes and because the treatments of Parkinson’s are not effective in ET. 

Did you know?

People with ET seem to be more vulnerable to the side effects of neuroleptic or antipsychotic drugs, readily producing Parkinson’s-type symptoms.  Often they do not remember or report that they are taking long term neuroleptics and may present to the doctor with features indistinguishable from classical Parkinson’s resulting in misdiagnosis. 

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