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Sunday, 05 February 2012
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Dementia and Parkinson's: Research papers
Mood disorders in Parkinson's disease
The development and validation of diagnostic criteria and rating scales for these disorders remain a priority particularly in relation to anxiety and apathy. Another gap in the management of these disorders is the limited empirical evidence for the treatment of these problems.
01 January 2012
Glucocerebrosidase mutations confer a greater risk of dementia during Parkinson's disease course
Study findings suggest that mutations in the glucocerebrosidase gene not only increase the risk of both Parkinson's disease and Lewy body dementia but also strongly influence the course of Parkinson's disease with respect to the appearance of dementia.
15 December 2011
A Novel Neurotrophic Drug for Cognitive Enhancement and Alzheimer's Disease
Using this approach, the authors identified an exceptionally potent, orally active, neurotrophic molecule that facilitates memory in normal rodents, and prevents the loss of synaptic proteins and cognitive decline in a transgenic AD mouse model.
14 December 2011
Dementia after DBS Surgery: A Case Report and Literature Review
This reports the case history of a 75-year-old woman with Parkinson's disease who developed severe cognitive problems after deep brain stimulation (DBS) of the bilateral subthalamic nuclei (STN).
01 December 2011
Dementia associated with Parkinson's disease: Applying the Movement Disorder Society Task Force criteria
Findings suggest that the MDS-TF criteria are more sensitive than the DSM-IV for a diagnosis of PDD. Old age, absence of psychiatric symptoms, and severe motor impairment can hinder the diagnosis of PDD.
20 June 2011
Parkinson's disease dementia can be easily detected in routine clinical practice
With an easy-to-use, short battery of tests that are commonly used in routine clinical practice, it is possible to diagnose PDD in accordance with reference criteria and with the same sensitivity and specificity as in a more extensive evaluation.
15 December 2010
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