Drooling and saliva management in Parkinson’s: Research papers
- Safety and efficacy of botulinum toxin type B for treatment of sialorrhea in Parkinson's: A prospective double-blind tri
The study concludes that intraglandular injection of botulinum toxin type B was safe, tolerable, and efficacious in treating sialorrhea in PD patients. Additional studies are warranted to further confirm the drug's robust efficacy, as well as evaluate its effect with repeated dosing.
01 September 2011
- Botulinum toxin A versus B in sialorrhea: A prospective, randomized, double-blind, crossover pilot study in patients with .....
Either 250 U Dysport or 2500 U Neurobloc have similar effectiveness and safety in controlling sialorrhea. BoNT-B has a shorter latency and comparable duration. Cost analysis, considering the doses used in this study protocol favored BoNT-B treatment.
21 January 2011
- Glycopyrrolate for sialorrhea in Parkinson disease: a randomized, double-blind, crossover trial
Sialorrhea affects approximately 75% of patients with Parkinson disease (PD). Sialorrhea is often treated with anticholinergics, but central side effects limit their usefulness.
16 April 2010
- Dysautonomia rating scales in Parkinson's disease: Sialorrhea, dysphagia, and constipationCritique and recommendations
The Movement Disorders Society commissioned a task force to assess available clinical rating scales, critique their clinimetric properties, and make recommendations regarding their clinical utility. Six clinical researchers and a biostatistician systematically searched the literature for scales of sialorrhea, dysphagia, and constipation, evaluated the scales' previous use, performance parameters, and quality of validation data (if available).
15 April 2009
- Sialorrhoea and drooling in patients with Parkinson's disease: epidemiology and management
Only a few well designed studies have been conducted to determine the optimal treatment for sialorrhoea in PD. A combination of approaches appears to be necessary to obtain successful results.
01 December 2008
- Parkinson's disease: a review and recommendations for dental management
Dental management of individuals with Parkinson's is a multifaceted challenge involving areas of preventive, restorative, and prosthetic dentistry. Support is also required for the psychosocial and behavioral aspects of this common progressive disorder.
28 June 2008
