Fatigue and Parkinson's: Research papers
- The Possible Clinical Predictors of Fatigue in PD: A Study of 135 Patients as Part of International NMS Scale Validation Project
In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson's disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.
01 December 2011
- Weekly exercise does not improve fatigue levels in Parkinson's disease
Sixty-five percent of the study group were fatigued (n = 24, mean 4.02, SD 1.48). Increased fatigue was associated with lower mobility and activity (P < .05). Individuals participated in a mean of 15 (SD 10) exercise sessions with no significant change in fatigue, mobility, well-being, or physical activity after exercise (P .05).
27 September 2011
- Does cardiovascular autonomic dysfunction contribute to fatigue in Parkinson's disease?
To clarify the involvement of autonomic dysfunction in fatigue in Parkinson's disease, the study conducted autonomic function tests on 33 patients with Parkinson's disease (mean age, 66.1 5.6 years; 20 men, 13 women) and evaluated their relationships to fatigue
15 August 2011
- Fatigue and excessive daytime sleepiness in idiopathic Parkinson's disease
To assess the frequency and severity of fatigue and excessive daytime sleepiness in patients with idiopathic PD and to study their relation to motor and non-motor symptoms and dopaminergic treatment.
13 May 2010
- Towards an understanding of fatigue in Parkinson disease
This study found fatigue to be primarily associated with symptoms of depression and anxiety, and with compromised motivation, parkinsonism (particularly axial/postural/gait impairment) and pain. These results are in agreement with findings in other disorders and imply that fatigue should be considered a separate PD entity differing from, for example, excessive daytime sleepiness.
01 May 2010
- Using Modafinil to Treat Fatigue in Parkinson Disease: A Double-Blind, Placebo-Controlled Pilot Study
To determine if modafinil improves subjective fatigue and physical fatigability in PD.
01 December 2009
