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Wednesday, 23 May 2012
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Pain in Parkinson's: Research papers
Prevalence of pain in Parkinson's: A systematic review using the modified QUADAS tool
Surprisingly, only 52.4% of PD patients with pain used analgesics, most often nonopioids. PD patients seem to be predisposed to develop pain and physicians should be aware of pain as a common feature of PD.
15 April 2012
Pain in Parkinson's disease
Increased understanding of basal ganglia pathways has provided further insights into the pathogenesis of pain in PD, but the exact mechanism of pain processing and modulation remains unclear.
15 April 2012
Parkinson disease, L-dopa, and neuropathy: Did we miss something?
This issue of Neurology() takes up the already controversial question of the increased prevalence of neuropathy in chronic levodopa-treated IPD and its potential but tenuous link to elevated plasma levels of homocysteine (Hcy) and methylmalonic acid (MMA) and to reduced vitamin B(12) levels.
02 November 2011
Pain sensitivity and clinical progression in Parkinson's disease
As Parkinson's disease-related pain can be an early symptom in Parkinson's disease, the present study aimed to investigate experimental pain sensitivity and spinal nociception during clinical progression.
15 October 2011
Facilitated temporal summation of pain at spinal level in Parkinson's disease
The increased gain in pain processing at spinal level in Parkinson's disease patients could be a consequence of the degenerative phenomena involving supraspinal projections implicated in the modulation of pain processing and could make Parkinson's disease patients more predisposed to develop a pain condition.
15 February 2011
Apomorphine effect on pain threshold in Parkinson's disease: A clinical and positron emission tomography study
In this randomized controlled double blind study, we compared the effect of apomorphine versus placebo on pain thresholds and pain-induced cerebral activity in 25 patients with PD.
15 January 2011
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